Dia-Interacting Protein Modulates Formin-Mediated Actin Assembly at the Cell Cortex
نویسندگان
چکیده
منابع مشابه
Cell-cycle regulation of formin-mediated actin cable assembly.
Assembly of appropriately oriented actin cables nucleated by formin proteins is necessary for many biological processes in diverse eukaryotes. However, compared with knowledge of how nucleation of dendritic actin filament arrays by the actin-related protein-2/3 complex is regulated, the in vivo regulatory mechanisms for actin cable formation are less clear. To gain insights into mechanisms for ...
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The physical interaction of the plasma membrane with the associated cortical cytoskeleton is important in many morphogenetic processes during development. At the end of the syncytial blastoderm of Drosophila the plasma membrane begins to fold in and forms the furrow canals in a regular hexagonal pattern. Every furrow canal leads the invagination of membrane between adjacent nuclei. Concomitantl...
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Eukaryotic cells are organized in three dimensions to allow for both cell division and for them to perform their physiological functions. This organization is dependent upon the arrangement of the cytoskeleton, which can either generate force by subunit polymerization or serve as tracks for molecular motors to deliver protein complexes, RNAs, or membrane-bound compartments. In general, long-ran...
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Tropomyosins comprise a large family of actin-binding proteins with critical roles in diverse actin-based processes [1], but our understanding of how they mechanistically contribute to actin filament dynamics has been limited. We addressed this question in S. cerevisiae, where tropomyosins (Tpm1 and Tpm2), profilin (Pfy1), and formins (Bni1 and Bnr1) are required for the assembly of an array of...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2007
ISSN: 0960-9822
DOI: 10.1016/j.cub.2007.03.024